Xgeva (Denosumab) is a medication primarily used to prevent bone loss and related complications in patients with advanced cancer. It’s particularly effective in preventing skeletal-related events (SREs) such as fractures, spinal cord compression, and the need for radiation therapy or surgery.
How it Works:
Denosumab, the active ingredient in Xgeva, works by targeting a specific protein called RANKL. This protein plays a crucial role in bone resorption, the process by which old bone tissue is broken down. By inhibiting RANKL, denosumab helps to slow down bone loss and strengthen bones.
Important Considerations:
- Side Effects: Common side effects of Xgeva include muscle pain, back pain, and fatigue. More serious side effects, such as hypocalcemia (low blood calcium levels), jawbone problems, and atypical femur fractures, can occur.
- Drug Interactions: Inform your doctor about all medications you’re taking, including over-the-counter drugs and herbal supplements, as they may interact with Xgeva.
- Pregnancy and Breastfeeding: Consult your doctor before taking Xgeva if you’re pregnant or breastfeeding.
- Medical Supervision: Xgeva should only be administered under the supervision of a healthcare professional.
Note: Always follow the instructions on the product label or consult a healthcare professional for specific advice. Xgeva is a prescription medication and should only be used under the supervision of a doctor.